SARMs, or selective androgen receptor modulators, have been around for a lot longer than most people realize. The first wave of SARMs was introduced in the 1940’s by Ligand Pharmaceuticals, and was marketed as a way to help treat cancer, osteoporosis, and other diseases. These were known as “steroidal SARMs.”
aIt wasn’t long before researchers discovered that these “steroidal SARMs” had a lot of side effects. Patients would often see huge gains in muscle, of up to 30 pounds within a matter of months. Needless to say, doctors very quickly realized that there were a number of negative side effects as well.
Steroids, and steroidal SARMs, often cause side effects such as gynecomastia, low libido, damaged to the liver, and heart disease. It was clear that doctors couldn’t continue prescribing these steroidal SARMs in their current form, so they were put on the shelf. Not much would be spoken of steroidal SARMs for decades.
Fast forward to the 1990’s however, and companies like GTx, Incorporated began to create “non-steroidal SARMs,” which are what we now simply call “SARMs.” Due to the protein-based chemical structure of these wonder drugs, they’re able to give us many of the benefits of steroids, with almost no side effects.